Endocrine Abstracts

Purpose: To assess the utility of BRAFV600E mutation detection in preoperative thyroid cancer diagnostic.Materials and methods: We studied 46 aspirates taken by FNA from patients with thyroid gland nodes. Thyroid tissue aspirates DNA was extracted by sorbent method. BRAF gene mutation was analyzed with primers specific for wild and mutant gen type by RT-PCR.Results: All patients were divided into three groups by cytological conclus...

There were evaluated galectin-3 expression in 66 fine-needle aspiration biopsy (FNAB) specimens from patients with thyroid gland nodules by flow cytometry method. We include in our study 29 patients with papillary thyroid cancer (PTC), 31 – with follicular neoplasia, 6 – with nodular colloid goiter by cytological examination. For specimens analysis, taken by FNAB of thyroid gland nodules, were used indirect immunofluorence method /Coons/.Result...